HIV-1 exploits the Fanconi anemia pathway for viral DNA integration.

Fu, Shaozu; Phan, An Thanh; Mao, Dexin; Wang, Xinlu; Gao, Guangxia; Goff, Stephen P; Zhu, Yiping

Fu, Shaozu; Phan, An Thanh; Mao, Dexin; Wang, Xinlu; Gao, Guangxia; Goff, Stephen P; Zhu, Yiping.

Afiliação

Fu S; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Phan AT; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Mao D; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Wang X; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Gao G; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address: gaogx@moon.ibp.ac.cn.
Goff SP; Department of Biochemistry and Molecular Biophysics and of Microbiology and Immunology, Columbia University, New York, NY 10032, USA. Electronic address: spg1@cumc.columbia.edu.
Zhu Y; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA. Electronic address: yiping_zhu@urmc.rochester.edu.

Cell Rep ; 39(8): 110840, 2022 05 24.

Article em En | MEDLINE | ID: mdl-35613597

Assuntos

Anemia de Fanconi; HIV-1; Dano ao DNA; Reparo do DNA; DNA Viral/genética; DNA Viral/metabolismo; Anemia de Fanconi/genética; Anemia de Fanconi/metabolismo; Proteína do Grupo de Complementação D2 da Anemia de Fanconi/metabolismo; Proteínas de Grupos de Complementação da Anemia de Fanconi/genética; Proteínas de Grupos de Complementação da Anemia de Fanconi/metabolismo; HIV-1/genética; HIV-1/metabolismo; Humanos; Ubiquitinação

Palavras-chave

CP: Microbiology; Fanconi anemia DNA repair pathway; HIV-1; integration

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: HIV-1 / Anemia de Fanconi Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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