NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species.

Harijith, Anantha; Basa, Prathima; Ha, Alison; Thomas, Jaya; Jafri, Anjum; Fu, Panfeng; MacFarlane, Peter M; Raffay, Thomas M; Natarajan, Viswanathan; Sudhadevi, Tara

Harijith, Anantha; Basa, Prathima; Ha, Alison; Thomas, Jaya; Jafri, Anjum; Fu, Panfeng; MacFarlane, Peter M; Raffay, Thomas M; Natarajan, Viswanathan; Sudhadevi, Tara.

Afiliação

Harijith A; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Basa P; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Ha A; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Thomas J; Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Jafri A; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Fu P; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
MacFarlane PM; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Raffay TM; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Natarajan V; Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.
Sudhadevi T; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago, Chicago, IL, United States.

Front Pharmacol ; 13: 880878, 2022.

Article em En | MEDLINE | ID: mdl-35662702

Palavras-chave

NADPH oxidase 4; alveolar type 2 epithelial cell; apoptosis; hyperoxic acute lung injury; mitochondrial ROS

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos