Comparison of mobility shift affinity capillary electrophoresis and capillary electrophoresis frontal analysis for binding constant determination between human serum albumin and small drugs.

Mlcochová, Hana; Ratih, Ratih; Michalcová, Lenka; Wätzig, Hermann; Glatz, Zdenek; Stein, Matthias

Mlcochová, Hana; Ratih, Ratih; Michalcová, Lenka; Wätzig, Hermann; Glatz, Zdenek; Stein, Matthias.

Afiliação

Mlcochová H; Institute of Medicinal and Pharmaceutical Chemistry, TU Braunschweig, Braunschweig, Lower Saxony, Germany.
Ratih R; Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.
Michalcová L; Institute of Medicinal and Pharmaceutical Chemistry, TU Braunschweig, Braunschweig, Lower Saxony, Germany.
Wätzig H; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Surabaya, Surabaya, East Java, Indonesia.
Glatz Z; Institute of Medicinal and Pharmaceutical Chemistry, TU Braunschweig, Braunschweig, Lower Saxony, Germany.
Stein M; Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.

Electrophoresis ; 43(16-17): 1724-1734, 2022 09.

Article em En | MEDLINE | ID: mdl-35704222

Assuntos

Isotacoforese; Leucemia Mieloide Aguda; Eletroforese Capilar/métodos; Humanos; Ibuprofeno; Ligação Proteica; Reprodutibilidade dos Testes; Albumina Sérica Humana/metabolismo; Triptofano

Palavras-chave

binding parameters; capillary electrophoresis-frontal analysis; drugs; human serum albumin; mobility shift affinity capillary electrophoresis

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Isotacoforese Limite: Humans Idioma: En Revista: Electrophoresis Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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