VH3-53/66-Class RBD-Specific Human Monoclonal Antibody iB20 Displays Cross-Neutralizing Activity against Emerging SARS-CoV-2 Lineages.

Kulemzin, Sergey V; Sergeeva, Maria V; Baranov, Konstantin O; Gorchakov, Andrey A; Guselnikov, Sergey V; Belovezhets, Tatyana N; Volkova, Olga Yu; Najakshin, Alexander M; Chikaev, Nikolai A; Danilenko, Daria M; Taranin, Alexander V

Kulemzin, Sergey V; Sergeeva, Maria V; Baranov, Konstantin O; Gorchakov, Andrey A; Guselnikov, Sergey V; Belovezhets, Tatyana N; Volkova, Olga Yu; Najakshin, Alexander M; Chikaev, Nikolai A; Danilenko, Daria M; Taranin, Alexander V.

Afiliação

Kulemzin SV; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Sergeeva MV; Smorodintsev Research Institute of Influenza, 197376 St. Petersburg, Russia.
Baranov KO; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Gorchakov AA; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Guselnikov SV; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Belovezhets TN; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Volkova OY; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Najakshin AM; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Chikaev NA; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Danilenko DM; Smorodintsev Research Institute of Influenza, 197376 St. Petersburg, Russia.
Taranin AV; Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia.

J Pers Med ; 12(6)2022 May 29.

Article em En | MEDLINE | ID: mdl-35743680

Palavras-chave

COVID-19; Omicron; SARS-CoV-2; VH1-58; VH3-53/66; iB14; iB20; mutational escape; neutralizing monoclonal antibodies; variants of concern

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: J Pers Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa