Synthesis, Anticancer Potential and Comprehensive Toxicity Studies of Novel Brominated Derivatives of Bacterial Biopigment Prodigiosin from <i>Serratia marcescens</i> ATCC 27117.

Lazic, Jelena; Skaro Bogojevic, Sanja; Vojnovic, Sandra; Aleksic, Ivana; Milivojevic, Dusan; Kretzschmar, Martin; Gulder, Tanja; Petkovic, Milos; Nikodinovic-Runic, Jasmina

Synthesis, Anticancer Potential and Comprehensive Toxicity Studies of Novel Brominated Derivatives of Bacterial Biopigment Prodigiosin from Serratia marcescens ATCC 27117.

Lazic, Jelena; Skaro Bogojevic, Sanja; Vojnovic, Sandra; Aleksic, Ivana; Milivojevic, Dusan; Kretzschmar, Martin; Gulder, Tanja; Petkovic, Milos; Nikodinovic-Runic, Jasmina.

Afiliação

Lazic J; Graduate School, University of Nova Gorica, SI-5000 Nova Gorica, Slovenia.
Skaro Bogojevic S; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.
Vojnovic S; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.
Aleksic I; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.
Milivojevic D; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.
Kretzschmar M; Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11000 Belgrade, Serbia.
Gulder T; Institute of Organic Chemistry, Leipzig University, 04103 Leipzig, Germany.
Petkovic M; Institute of Organic Chemistry, Leipzig University, 04103 Leipzig, Germany.
Nikodinovic-Runic J; Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.

Molecules ; 27(12)2022 Jun 09.

Article em En | MEDLINE | ID: mdl-35744855

Assuntos

Neoplasias; Prodigiosina; Animais; Apoptose; Prodigiosina/metabolismo; Prodigiosina/farmacologia; Serratia marcescens/metabolismo; Peixe-Zebra/metabolismo

Palavras-chave

Serratia; anticancer activity; bromination; embryotoxicity; halogenation; prodigiosin; zebrafish

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Prodigiosina / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Eslovênia

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