Distribution of pediatric keratoconus by different age and gender groups.
Front Pediatr
; 10: 937246, 2022.
Article
em En
| MEDLINE
| ID: mdl-35923788
ABSTRACT
Purpose:
To evaluate the distribution of pediatric keratoconus patients and the disease severity based on different age and gender groups in China. Materials andmethods:
A total of 446 keratoconus eyes in 266 pediatric patients from January 2019 to January 2022 were included in the cross-sectional study. The clinical findings and severity of keratoconus were recorded and Kruskal-Wallis test, chi-squared test, and Cochran-Mantel-Haenszel (CMH) test were used to compare the parameters between different gender and age groups.Results:
The male/female ratio was 353/93 (3.81), and the median age was 16 years (range 6-17 years). Male patients were statistically younger than female patients (P = 0.041). The male/female ratio decreased with age (P for trend = 0.011). The distribution of the topographic keratoconus classification (TKC) stage was significantly different between gender and age groups (all P < 0.05). Male patients had a higher ratio of advanced keratoconus eyes (TKC ≥ 3) than female patients (P < 0.001), and CMH analysis indicated that being a male was a risk factor for advanced keratoconus after controlling for age (odds ratio 2.581, P < 0.001).Conclusion:
Male keratoconus patients were younger, with a higher ratio of advanced keratoconus than female patients in the Chinese pediatric patients evaluated. Multicenter studies with larger sample sizes are necessary in the future.
Texto completo:
1
Bases de dados:
MEDLINE
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Front Pediatr
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China