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Persistent DNA damage underlies tubular cell polyploidization and progression to chronic kidney disease in kidneys deficient in the DNA repair protein FAN1.
Airik, Merlin; Phua, Yu Leng; Huynh, Amy B; McCourt, Blake T; Rush, Brittney M; Tan, Roderick J; Vockley, Jerry; Murray, Susan L; Dorman, Anthony; Conlon, Peter J; Airik, Rannar.
Afiliação
  • Airik M; Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Phua YL; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Huynh AB; Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • McCourt BT; Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Rush BM; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Tan RJ; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Vockley J; Division of Genetic and Genomic Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Murray SL; Department of Nephrology, Beaumont Hospital and Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Dorman A; Department of Nephrology, Beaumont Hospital and Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Conlon PJ; Department of Nephrology, Beaumont Hospital and Royal College of Surgeons in Ireland, Dublin, Ireland.
  • Airik R; Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA; Department of Developmental Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address: airikr@pitt.edu.
Kidney Int ; 102(5): 1042-1056, 2022 11.
Article em En | MEDLINE | ID: mdl-35931300
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Nefrite Intersticial Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Kidney Int Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Insuficiência Renal Crônica / Nefrite Intersticial Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Kidney Int Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos