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Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial.
Yamazaki, Tomoko; Gunderson, Andrew J; Gilchrist, Miranda; Whiteford, Mark; Kiely, Maria X; Hayman, Amanda; O'Brien, David; Ahmad, Rehan; Manchio, Jeffrey V; Fox, Nathaniel; McCarty, Kayla; Phillips, Michaela; Brosnan, Evelyn; Vaccaro, Gina; Li, Rui; Simon, Miklos; Bernstein, Eric; McCormick, Mary; Yamasaki, Lena; Wu, Yaping; Drokin, Ashley; Carnahan, Trevor; To, Yy; Redmond, William L; Lee, Brian; Louie, Jeannie; Hansen, Eric; Solhjem, Matthew C; Cramer, Julie; Urba, Walter J; Gough, Michael J; Crittenden, Marka R; Young, Kristina H.
Afiliação
  • Yamazaki T; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Gunderson AJ; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Gilchrist M; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA; ThemoFisher, Hillsboro, OR, USA.
  • Whiteford M; Colon and Rectal Surgery Division, The Oregon Clinic, Portland, OR, USA.
  • Kiely MX; Colon and Rectal Surgery Division, The Oregon Clinic, Portland, OR, USA.
  • Hayman A; Colon and Rectal Surgery Division, The Oregon Clinic, Portland, OR, USA.
  • O'Brien D; Colon and Rectal Surgery Division, The Oregon Clinic, Portland, OR, USA.
  • Ahmad R; Colon and Rectal Surgery Division, The Oregon Clinic, Portland, OR, USA.
  • Manchio JV; Colorectal Health Northwest, Portland, OR, USA.
  • Fox N; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • McCarty K; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Phillips M; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Brosnan E; Providence Cancer Center Oncology and Hematology Care Clinic, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Vaccaro G; Providence Cancer Center Oncology and Hematology Care Clinic, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Li R; Providence Cancer Center Oncology and Hematology Care Clinic, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Simon M; Compass Oncology, Portland, OR, USA.
  • Bernstein E; Providence Cancer Center Oncology and Hematology Care Clinic, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • McCormick M; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Yamasaki L; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Wu Y; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Drokin A; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Carnahan T; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • To Y; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Redmond WL; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Lee B; Radiation Oncology Division, The Oregon Clinic, Portland, OR, USA.
  • Louie J; Radiation Oncology Division, The Oregon Clinic, Portland, OR, USA.
  • Hansen E; Radiation Oncology Division, The Oregon Clinic, Portland, OR, USA.
  • Solhjem MC; Radiation Oncology Division, The Oregon Clinic, Portland, OR, USA.
  • Cramer J; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Urba WJ; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA; Providence Cancer Center Oncology and Hematology Care Clinic, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Gough MJ; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA.
  • Crittenden MR; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA; Radiation Oncology Division, The Oregon Clinic, Portland, OR, USA.
  • Young KH; Earle A Chiles Research Institute, Providence Cancer Institute of Oregon, Portland, OR, USA; Radiation Oncology Division, The Oregon Clinic, Portland, OR, USA. Electronic address: kristina.young@providence.org.
Lancet Oncol ; 23(9): 1189-1200, 2022 09.
Article em En | MEDLINE | ID: mdl-35952709

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Retais / Adenocarcinoma / Segunda Neoplasia Primária Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Retais / Adenocarcinoma / Segunda Neoplasia Primária Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos