Gliotransmission of D-serine promotes thirst-directed behaviors in Drosophila.

Park, Annie; Croset, Vincent; Otto, Nils; Agarwal, Devika; Treiber, Christoph D; Meschi, Eleonora; Sims, David; Waddell, Scott

Park, Annie; Croset, Vincent; Otto, Nils; Agarwal, Devika; Treiber, Christoph D; Meschi, Eleonora; Sims, David; Waddell, Scott.

Afiliação

Park A; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK.
Croset V; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK; Department of Biosciences, Durham University, Durham DH1 3LE, UK. Electronic address: vincent.croset@durham.ac.uk.
Otto N; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK.
Agarwal D; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK; MRC Computational Genomics Analysis and Training Programme (CGAT), MRC Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.
Treiber CD; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK.
Meschi E; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK.
Sims D; MRC Computational Genomics Analysis and Training Programme (CGAT), MRC Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.
Waddell S; Centre for Neural Circuits & Behaviour, University of Oxford, Oxford OX1 3TA, UK. Electronic address: scott.waddell@cncb.ox.ac.uk.

Curr Biol ; 32(18): 3952-3970.e8, 2022 09 26.

Article em En | MEDLINE | ID: mdl-35963239

Assuntos

Serina; Transmissão Sináptica; Animais; Astrócitos/metabolismo; Drosophila/metabolismo; Ácido Glutâmico/metabolismo; N-Metilaspartato/metabolismo; Receptores de Glutamato/metabolismo; Receptores de N-Metil-D-Aspartato/metabolismo; Serina/metabolismo; Transmissão Sináptica/fisiologia; Sede; Água/metabolismo

Palavras-chave

D-serine; Drosophila; NMDA receptors; astrocytes; behavior; glia; gliotransmission; single-cell transcriptomics; thirst; water procurement

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Serina / Transmissão Sináptica Limite: Animals Idioma: En Revista: Curr Biol Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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