Development of a cell line-based in vitro assay for assessment of Diphtheria, Tetanus and acellular Pertussis (DTaP)-induced inflammasome activation.

Vandebriel, Rob J; Stalpers, Coen A L; Vermeulen, Jolanda P; Remkes, Mariska; Schmelter, Marit; Broere, Femke; Hoefnagel, Marcel H N

Vandebriel, Rob J; Stalpers, Coen A L; Vermeulen, Jolanda P; Remkes, Mariska; Schmelter, Marit; Broere, Femke; Hoefnagel, Marcel H N.

Afiliação

Vandebriel RJ; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, the Netherlands. Electronic address: rob.vandebriel@rivm.nl.
Stalpers CAL; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, the Netherlands; Faculty of Veterinary Medicine, Department of Biomolecular Health Sciences, Utrecht University, Utrecht, Netherlands; Quality Department, Medicines Evaluation Board, Utrecht, the Nethe
Vermeulen JP; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Remkes M; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Schmelter M; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Broere F; Faculty of Veterinary Medicine, Department of Biomolecular Health Sciences, Utrecht University, Utrecht, Netherlands; Faculty of Veterinary Medicine, Department of Clinical Sciences, Utrecht University, Utrecht, Netherlands.
Hoefnagel MHN; Quality Department, Medicines Evaluation Board, Utrecht, the Netherlands.

Vaccine ; 40(38): 5601-5607, 2022 09 09.

Article em En | MEDLINE | ID: mdl-35999078

Assuntos

Vacinas contra Difteria, Tétano e Coqueluche Acelular; Difteria; Tétano; Coqueluche; Adjuvantes Imunológicos/farmacologia; Alumínio; Hidróxido de Alumínio/farmacologia; Anticorpos Antibacterianos; Linhagem Celular; Difteria/prevenção & controle; Vacina contra Difteria, Tétano e Coqueluche; Humanos; Inflamassomos; Proteína 3 que Contém Domínio de Pirina da Família NLR; Vacina contra Coqueluche; Tétano/prevenção & controle; Coqueluche/prevenção & controle

Palavras-chave

Adjuvant; Aluminium hydroxide; Aluminium phosphate; Consistency approach; Inflammasome; NLRP3

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Tétano / Coqueluche / Vacinas contra Difteria, Tétano e Coqueluche Acelular / Difteria Limite: Humans Idioma: En Revista: Vaccine Ano de publicação: 2022 Tipo de documento: Article

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