Sex and gender differences in movement disorders: Parkinson's disease, essential tremor, dystonia and chorea.
Int Rev Neurobiol
; 164: 101-128, 2022.
Article
em En
| MEDLINE
| ID: mdl-36038202
ABSTRACT
Sex and gender-based differences in epidemiology, clinical features and therapeutical responses are emerging in several movement disorders, even though they are still not widely recognized. In this chapter, we summarize the most relevant evidence concerning these differences in Parkinson's disease, essential tremor, dystonia and chorea. Indeed, both sex-related biological (hormonal levels fluctuations) and gender-related variables (socio-cultural and environmental factors) may differently impact symptoms manifestation and severity, phenotype and disease progression of movement disorders on men and women. Moreover, sex differences in treatment responses should be taken into account in any therapeutical planning. Physicians need to be aware of these major differences between men and women that will eventually have a major impact on better tailoring prevention, treatment, or even delaying progression of the most common movement disorders.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Coreia
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Distúrbios Distônicos
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Tremor Essencial
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Distonia
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Transtornos dos Movimentos
Tipo de estudo:
Diagnostic_studies
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
Int Rev Neurobiol
Ano de publicação:
2022
Tipo de documento:
Article