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Acute frataxin knockdown in induced pluripotent stem cell-derived cardiomyocytes activates a type I interferon response.
Cotticelli, M Grazia; Xia, Shujuan; Truitt, Rachel; Doliba, Nicolai M; Rozo, Andrea V; Tobias, John W; Lee, Taehee; Chen, Justin; Napierala, Jill S; Napierala, Marek; Yang, Wenli; Wilson, Robert B.
Afiliação
  • Cotticelli MG; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Xia S; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Truitt R; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Doliba NM; Institute of Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Rozo AV; Institute of Diabetes, Obesity, and Metabolism, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Tobias JW; Department of Genetics, Penn Genomics Analysis Core, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lee T; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Chen J; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Napierala JS; Department of Neurology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Napierala M; Department of Neurology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Yang W; Department of Medicine, Division of Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Wilson RB; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Dis Model Mech ; 16(5)2023 05 01.
Article em En | MEDLINE | ID: mdl-36107856

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ataxia de Friedreich / Interferon Tipo I / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ataxia de Friedreich / Interferon Tipo I / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos