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A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice.
Schmitt, Erica G; Toth, Kelsey A; Risma, Samuel I; Kolicheski, Ana; Saucier, Nermina; Berríos, Rafael J Feliciano; Greenberg, Zev J; Leiding, Jennifer W; Bleesing, Jack J; Thatayatikom, Akaluck; Schuettpelz, Laura G; Edwards, John R; Vogel, Tiphanie P; Cooper, Megan A.
Afiliação
  • Schmitt EG; Department of Pediatrics, Division of Rheumatology and Immunology.
  • Toth KA; Department of Pediatrics, Division of Rheumatology and Immunology.
  • Risma SI; Department of Pediatrics, Division of Rheumatology and Immunology.
  • Kolicheski A; Department of Pediatrics, Division of Rheumatology and Immunology.
  • Saucier N; Department of Pediatrics, Division of Rheumatology and Immunology.
  • Berríos RJF; Center for Pharmacogenomics, Department of Medicine, and.
  • Greenberg ZJ; Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Leiding JW; Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland.
  • Bleesing JJ; Infectious Diseases and Immunology, Arnold Palmer Hospital for Children, Orlando, Florida, USA.
  • Thatayatikom A; Division of BM Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Schuettpelz LG; AdventHealth for Children, Orlando, Florida, USA.
  • Edwards JR; Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Vogel TP; Center for Pharmacogenomics, Department of Medicine, and.
  • Cooper MA; Division of Rheumatology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas, USA.
JCI Insight ; 7(21)2022 11 08.
Article em En | MEDLINE | ID: mdl-36136607
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Linfócitos T Reguladores / Mutação com Ganho de Função Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Linfócitos T Reguladores / Mutação com Ganho de Função Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: JCI Insight Ano de publicação: 2022 Tipo de documento: Article