Reversal of multidrug resistance by Fissistigma latifolium-derived chalconoid 2-hydroxy-4,5,6-trimethoxydihydrochalcone in cancer cell lines overexpressing human P-glycoprotein.

Teng, Yu-Ning; Hung, Chin-Chuan; Kao, Pei-Heng; Chang, Ying-Tzu; Lan, Yu-Hsuan

Teng, Yu-Ning; Hung, Chin-Chuan; Kao, Pei-Heng; Chang, Ying-Tzu; Lan, Yu-Hsuan.

Afiliação

Teng YN; School of Medicine, College of Medicine, I-Shou University, 8 Yida Road, Kaohsiung 82445, Taiwan, ROC. Electronic address: eunicegh520@gmail.com.
Hung CC; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan ROC; Department of Pharmacy, China Medical University Hospital, 2 Yude Road, Taichung 40447, Taiwan, ROC; Department of Healthcare Administration, Asia Unive
Kao PH; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan ROC. Electronic address: u104003308@cmu.edu.tw.
Chang YT; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan ROC. Electronic address: tel22336978@hotmail.com.
Lan YH; Department of Pharmacy, College of Pharmacy, China Medical University, 100, Section 1, Jingmao Rd., Beitun Dist., Taichung City 406040, Taiwan ROC. Electronic address: lanyh@mail.cmu.edu.tw.

Biomed Pharmacother ; 156: 113832, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36242847

Assuntos

Annonaceae; Chalconas; Neoplasias; Humanos; Chalconas/farmacologia; Resistencia a Medicamentos Antineoplásicos; Subfamília B de Transportador de Cassetes de Ligação de ATP/metabolismo; Linhagem Celular Tumoral; Resistência a Múltiplos Medicamentos; Transportadores de Cassetes de Ligação de ATP/metabolismo; Adenosina Trifosfatases/metabolismo; Doxorrubicina/farmacologia; Neoplasias/tratamento farmacológico

Palavras-chave

2-hydroxy-4; 5; 6-trimethoxydihydrochalcone; Cancer multi-drug resistance; Dihydrochalcone; Fissistigma latifolium; Human P-gp

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Annonaceae / Chalconas / Neoplasias Limite: Humans Idioma: En Revista: Biomed Pharmacother Ano de publicação: 2022 Tipo de documento: Article

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