Co-amorphous Systems of Sinomenine with Platensimycin or Sulfasalazine: Physical Stability and Excipient-Adjusted Release Behavior.

Chen, Xin; Li, Duanxiu; Zhang, Hailu; Duan, Yanwen; Huang, Yong

Chen, Xin; Li, Duanxiu; Zhang, Hailu; Duan, Yanwen; Huang, Yong.

Afiliação

Chen X; Xiangya International Academy of Translational Medicine, Central South University, Changsha, Hunan410013, PR China.
Li D; Laboratory of Magnetic Resonance Spectroscopy and Imaging, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou215123, PR China.
Zhang H; Guangdong Institute of Semiconductor Micro-Nano Manufacturing Technology, Foshan528200, PR China.
Duan Y; Laboratory of Magnetic Resonance Spectroscopy and Imaging, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou215123, PR China.
Huang Y; Xiangya International Academy of Translational Medicine, Central South University, Changsha, Hunan410013, PR China.

Mol Pharm ; 19(11): 4370-4381, 2022 11 07.

Article em En | MEDLINE | ID: mdl-36251509

Assuntos

Excipientes; Sulfassalazina; Excipientes/química; Estabilidade de Medicamentos; Solubilidade; Varredura Diferencial de Calorimetria; Difração de Raios X; Espectroscopia de Infravermelho com Transformada de Fourier

Palavras-chave

co-amorphous systems; hydrogen bonding interactions; infection-associated rheumatoid arthritis; platensimycin; sinomenine; sulfasalazine

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Sulfassalazina / Excipientes Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article

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