Aberrant p53 expression is associated with neoplastic progression in Barrett oesophagus diagnosed as indefinite for dysplasia.

Chen, Xiuxu; Liu, Bella Lingjia; Harpaz, Noam; Zhu, Hongfa; Polydorides, Alexandros D; Liu, Qingqing

Chen, Xiuxu; Liu, Bella Lingjia; Harpaz, Noam; Zhu, Hongfa; Polydorides, Alexandros D; Liu, Qingqing.

Afiliação

Chen X; Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Liu BL; Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Harpaz N; Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zhu H; Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Polydorides AD; Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Liu Q; Department of Pathology, Molecular & Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Histopathology ; 82(3): 454-465, 2023 Feb.

Article em En | MEDLINE | ID: mdl-36251540

Assuntos

Adenocarcinoma; Esôfago de Barrett; Neoplasias Esofágicas; Lesões Pré-Cancerosas; Adulto; Idoso; Idoso de 80 Anos ou mais; Humanos; Masculino; Pessoa de Meia-Idade; Adenocarcinoma/patologia; Esôfago de Barrett/diagnóstico; Esôfago de Barrett/patologia; Progressão da Doença; Neoplasias Esofágicas/diagnóstico; Neoplasias Esofágicas/patologia; Hiperplasia; Lesões Pré-Cancerosas/diagnóstico; Lesões Pré-Cancerosas/patologia; Proteína Supressora de Tumor p53; Feminino

Palavras-chave

Barrett oesophagus; high-grade dysplasia; indefinite for dysplasia; low-grade dysplasia; oesophageal adenocarcinoma; p53

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Lesões Pré-Cancerosas / Esôfago de Barrett / Neoplasias Esofágicas / Adenocarcinoma Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Histopathology Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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