Synthesis of Heterobenzyl Sulfoxides Enabled by Palladium-Catalyzed Allylic Alkylation of Sulfenate Anions with Allenamides.
J Org Chem
; 87(21): 14646-14656, 2022 Nov 04.
Article
em En
| MEDLINE
| ID: mdl-36286625
A highly efficient palladium-catalyzed allenamide allylic alkylation of sulfenate anions under mild conditions is demonstrated. The present methodology provides a practical protocol to access various sulfoxide-containing heterocyclic compounds. The salient features of this transformation include a broad substrate scope, good functional group tolerance, easy to scale-up, and ready synthetic transformation.
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Bases de dados:
MEDLINE
Tipo de estudo:
Guideline
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China