Structure and Mechanism of Plant DNA Methyltransferases.
Adv Exp Med Biol
; 1389: 137-157, 2022.
Article
em En
| MEDLINE
| ID: mdl-36350509
ABSTRACT
DNA methylation is an important epigenetic mark conserved in eukaryotes from fungi to animals and plants, where it plays a crucial role in regulating gene expression and transposon silencing. Once the methylation mark is established by de novo DNA methyltransferases, specific regulatory mechanisms are required to maintain the methylation state during chromatin replication, both during meiosis and mitosis. Plant DNA methylation is found in three contexts; CG, CHG, and CHH (H = A, T, C), which are established and maintained by a unique set of DNA methyltransferases and are regulated by plant-specific pathways. DNA methylation in plants is often associated with other epigenetic modifications, such as noncoding RNA and histone modifications. This chapter focuses on the structure, function, and regulatory mechanism of plant DNA methyltransferases and their crosstalk with other epigenetic pathways.
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Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Arabidopsis
/
Metilação de DNA
Limite:
Animals
Idioma:
En
Revista:
Adv Exp Med Biol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos