Omics goes spatial epigenomics.

Schueder, Florian; Bewersdorf, Joerg

Schueder, Florian; Bewersdorf, Joerg.

Afiliação

Schueder F; Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA; Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, USA.
Bewersdorf J; Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA; Department of Biomedical Engineering, Yale University, New Haven, CT, USA; Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT, USA; Nanobiology Institute, Yale University, West Haven, CT, USA; Department of Physics, Yale University, New Haven, CT, USA. Electronic address: joerg.bewersdorf@yale.edu.

Cell ; 185(23): 4253-4255, 2022 11 10.

Article em En | MEDLINE | ID: mdl-36368304

ABSTRACT

ABSTRACT

Spatial omics techniques generate spatially resolved, comprehensive data about molecules that define the identity and function of cells in tissues. Epigenetic multiplexing approaches such as Multiplexed Error-robust FISH (MERFISH), introduced by Lu et al.1 in this issue of Cell, now allows researchers to study the epigenomic regulation of gene expression in a tissue-region specific manner.

Assuntos

Epigenômica; Análise de Célula Única; Epigenômica/métodos; Análise de Célula Única/métodos; Perfilação da Expressão Gênica/métodos; Hibridização in Situ Fluorescente/métodos

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Análise de Célula Única / Epigenômica Idioma: En Revista: Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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