Comparative analysis of somatostatin analog uptake between successfully irradiated and non-irradiated meningiomas.
Einstein (Sao Paulo)
; 20: eAO0104, 2022.
Article
em En
| MEDLINE
| ID: mdl-36449758
ABSTRACT
OBJECTIVE:
To evaluate whether there is a significant difference in somatostatin analog uptake in meningiomas treated or not with radiation therapy.METHODS:
A cross-sectional study was performed comparing measurements of somatostatin analog (68Ga-DOTATATE) uptake in two independent groups of ten patients each - one consisting of patients with meningiomas previously treated with radiation therapy and another comprising patients who had never been submitted to radiation therapy. All patients underwent PET/CT and MRI scans in an interval shorter than 24 hours between exams.RESULTS:
A total of 32 meningiomas from 20 patients were analyzed, all presenting significant somatostatin analog uptake in different degrees. The uptake levels of somatostatin analog were similar between the lesions treated or not with radiation therapy, and the mean values of SUVmax were 27.62 and 24.82, respectively (p=0.722). For SUVmean, the values were 16.20 and 14.82, respectively (p=0.822).CONCLUSION:
Comparative analysis between the groups showed no significant differences in degree of somatostatin analog uptake in successfully irradiated and non-irradiated meningiomas.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Meníngeas
/
Meningioma
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Einstein (Sao Paulo)
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Brasil