Autoreactivity and broad neutralization of antibodies against HIV-1 are governed by distinct mutations: Implications for vaccine design strategies.

Li, Xiaojun; Liao, Dongmei; Li, Zhengyang; Li, Jixi; Diaz, Marilyn; Verkoczy, Laurent; Gao, Feng

Li, Xiaojun; Liao, Dongmei; Li, Zhengyang; Li, Jixi; Diaz, Marilyn; Verkoczy, Laurent; Gao, Feng.

Afiliação

Li X; Department of Medicine, Duke University Medical Center, Durham, NC, United States.
Liao D; Department of Immunology, Duke University Medical Center, Durham, NC, United States.
Li Z; School of Life Sciences, Fudan University, Shanghai, China.
Li J; School of Life Sciences, Fudan University, Shanghai, China.
Diaz M; Applied Biomedical Science Institute, San Diego, CA, United States.
Verkoczy L; Applied Biomedical Science Institute, San Diego, CA, United States.
Gao F; Department of Medicine, Duke University Medical Center, Durham, NC, United States.

Front Immunol ; 13: 977630, 2022.

Article em En | MEDLINE | ID: mdl-36479128

Assuntos

HIV-1; Vacinas; HIV-1/genética

Palavras-chave

HIV-1; autoreactivity; broadly neutralizing antibody; mutation; poly reactivity

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Vacinas / HIV-1 Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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