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Synthesis and pharmacokinetic properties of novel cPLA2α inhibitors with 1-(carboxyalkylpyrrolyl)-3-aryloxypropan-2-one structure.
Subeska, Angelina; Althaus, Jan; Hake, Theresa; Hanekamp, Walburga; Bettenworth, Dominik; Mulac, Dennis; Langer, Klaus; Lehr, Matthias.
Afiliação
  • Subeska A; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstrasse 48, 48149 Münster, Germany.
  • Althaus J; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstrasse 48, 48149 Münster, Germany.
  • Hake T; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstrasse 48, 48149 Münster, Germany.
  • Hanekamp W; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstrasse 48, 48149 Münster, Germany.
  • Bettenworth D; Department of Medicine B, University Hospital Münster, 48149 Münster, Germany.
  • Mulac D; Institute of Pharmaceutical Technology and Biopharmacy, University of Münster, Corrensstrasse 48, 48149 Münster, Germany.
  • Langer K; Institute of Pharmaceutical Technology and Biopharmacy, University of Münster, Corrensstrasse 48, 48149 Münster, Germany.
  • Lehr M; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstrasse 48, 48149 Münster, Germany. Electronic address: lehrm@uni-muenster.de.
Bioorg Med Chem ; 77: 117110, 2023 01 01.
Article em En | MEDLINE | ID: mdl-36495814

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fosfolipases A2 do Grupo IV Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Fosfolipases A2 do Grupo IV Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha