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Fast tuning of observer-based circadian phase estimator using biometric data.
Ike, Chukwuemeka O; Wen, John T; Oishi, Meeko M K; Brown, Lee K; Agung Julius, A.
Afiliação
  • Ike CO; Lighting Enabled Systems and Applications (LESA) Engineering Research Center, Troy, NY, United States.
  • Wen JT; Department of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, United States.
  • Oishi MMK; Lighting Enabled Systems and Applications (LESA) Engineering Research Center, Troy, NY, United States.
  • Brown LK; Department of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, United States.
  • Agung Julius A; Department of Internal Medicine and School of Engineering, University of New Mexico, Albuquerque, NM, United States.
Heliyon ; 8(12): e12500, 2022 Dec.
Article em En | MEDLINE | ID: mdl-36636209
ABSTRACT
Circadian rhythms play a vital role in maintaining an individual's well-being, and they have been shown to be the product of the master oscillator in the suprachiasmatic nuclei (SCN) located in the brain. The SCN however, is inaccessible for assessment, so existing standards for circadian phase estimation often focus on the use of indirect measurements as proxies for the circadian state. These methods often suffer from severe delays due to invasive methods of sample collection, making online estimation impossible. In this paper, we propose a linear state observer as an elegant solution for continuous phase estimation. This observer-based filter is used in isolating the frequency components of input biometric signals, which are then taken to be the circadian state. We start the design process by fixing the observer's oscillatory frequency at 24 hours, and then we tune its gains using an evolutionary optimization algorithm to extract the target components from individuals' data. The resulting filter was able to provide phase estimates with an average absolute error within 1.5 hours on all test subjects, given their minute-to-minute actigraphy data collected in ambulatory conditions.
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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Heliyon Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Heliyon Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos