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A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection.
Heisler, David B; Johnson, Kristen A; Ma, Duo H; Ohlson, Maikke B; Zhang, Lishu; Tran, Michelle; Corley, Chase D; Abrams, Michael E; McDonald, Jeffrey G; Schoggins, John W; Alto, Neal M; Radhakrishnan, Arun.
Afiliação
  • Heisler DB; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Johnson KA; Department of Molecular Genetics, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Ma DH; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Ohlson MB; Department of Molecular Genetics, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Zhang L; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Tran M; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Corley CD; Department of Molecular Genetics, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Abrams ME; Department of Molecular Genetics, The University of Texas Southwestern Medical Center, Dallas, United States.
  • McDonald JG; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Schoggins JW; Department of Molecular Genetics, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Alto NM; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
  • Radhakrishnan A; Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, United States.
Elife ; 122023 01 25.
Article em En | MEDLINE | ID: mdl-36695568

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Zika virus / Infecção por Zika virus / Oxisteróis Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Zika virus / Infecção por Zika virus / Oxisteróis Limite: Animals / Humans Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos