Development and validation of circulating protein signatures as diagnostic biomarkers for biliary tract cancer.

Christensen, Troels D; Maag, Emil; Larsen, Ole; Feltoft, Claus L; Nielsen, Kaspar René; Jensen, Lars Henrik; Leerhøy, Bonna; Hansen, Carsten P; Chen, Inna M; Nielsen, Dorte L; Johansen, Julia S

Christensen, Troels D; Maag, Emil; Larsen, Ole; Feltoft, Claus L; Nielsen, Kaspar René; Jensen, Lars Henrik; Leerhøy, Bonna; Hansen, Carsten P; Chen, Inna M; Nielsen, Dorte L; Johansen, Julia S.

Afiliação

Christensen TD; Deparment of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Denmark.
Maag E; BioXpedia, Aarhus, Denmark.
Larsen O; Deparment of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Denmark.
Feltoft CL; Department of Medicine, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Denmark.
Nielsen KR; Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark.
Jensen LH; Department of Oncology, University Hospital of Southern Denmark, Vejle, Denmark.
Leerhøy B; Digestive Disease Center, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Hansen CP; Department of Surgery, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Chen IM; Deparment of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Denmark.
Nielsen DL; Deparment of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Denmark.
Johansen JS; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

JHEP Rep ; 5(3): 100648, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36699667

Palavras-chave

AUC, area under receiver-operating characteristic curve; BBTD, benign biliary tract disease; BP, best point; BTC, biliary tract cancer; CA19-9, carbohydrate antigen 19-9; CAIX, carbonic anhydrase IX; CASP8, caspase 8; CCA, cholangiocarcinoma; CCL, chemokine (C-C motif) ligand; CXCR, C-X-C motif chemokine; EDTA, ethylenediaminetetraacetic acid; GBC, gall bladder cancer; I-O, immuno-oncology; IL, interleukin; MMP-, matrix metalloproteinase-; NPX, normalized protein expression; TME, tumor microenvironment; biliary tract cancer; blood protein assay; cholangiocarcinoma; dCCA, distal cholangiocarcinoma; diagnosis; gall bladder cancer; iCCA, intrahepatic cholangiocarcinoma; multi-biomarker signature; pCCA, perihilar cholangiocarcinoma

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Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: JHEP Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca

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