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Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration.
Nollet, Edgar E; Duursma, Inez; Rozenbaum, Anastasiya; Eggelbusch, Moritz; Wüst, Rob C I; Schoonvelde, Stephan A C; Michels, Michelle; Jansen, Mark; van der Wel, Nicole N; Bedi, Kenneth C; Margulies, Kenneth B; Nirschl, Jeff; Kuster, Diederik W D; van der Velden, Jolanda.
Afiliação
  • Nollet EE; Department of Physiology, Amsterdam UMC, Location VUmc, O2 Science building-11W53, De Boelelaan 1108, 1081HZ Amsterdam, The Netherlands.
  • Duursma I; Amsterdam Cardiovascular Sciences, Heart failure & Arrhythmias, Amsterdam UMC, Location VUmc, O2 Science building, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
  • Rozenbaum A; Department of Physiology, Amsterdam UMC, Location VUmc, O2 Science building-11W53, De Boelelaan 1108, 1081HZ Amsterdam, The Netherlands.
  • Eggelbusch M; Amsterdam Cardiovascular Sciences, Heart failure & Arrhythmias, Amsterdam UMC, Location VUmc, O2 Science building, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
  • Wüst RCI; Department of Physiology, Amsterdam UMC, Location VUmc, O2 Science building-11W53, De Boelelaan 1108, 1081HZ Amsterdam, The Netherlands.
  • Schoonvelde SAC; Amsterdam Cardiovascular Sciences, Heart failure & Arrhythmias, Amsterdam UMC, Location VUmc, O2 Science building, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
  • Michels M; Laboratory for Myology, Faculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Jansen M; Department of Nutrition and Dietetics, Amsterdam UMC, Amsterdam, The Netherlands.
  • van der Wel NN; Faculty of Sports and Nutrition, Center of Expertise Urban Vitality, Amsterdam University of Applied Sciences, Amsterdam, The Netherlands.
  • Bedi KC; Laboratory for Myology, Faculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Margulies KB; Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
  • Nirschl J; Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands.
  • Kuster DWD; Division of Genetics, UMC Utrecht, Utrecht, The Netherlands.
  • van der Velden J; Department of Medical Biology, Electron Microscopy Centre, Amsterdam UMC, Amsterdam, The Netherlands.
Eur Heart J ; 44(13): 1170-1185, 2023 04 01.
Article em En | MEDLINE | ID: mdl-36734059

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Cardiomiopatia Hipertrófica / Miócitos Cardíacos Limite: Humans Idioma: En Revista: Eur Heart J Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Cardiomiopatia Hipertrófica / Miócitos Cardíacos Limite: Humans Idioma: En Revista: Eur Heart J Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda