Preferential Adsorption of Ethylene Oxide on Fe and Chlorine on Ni Enabled Scalable Electrosynthesis of Ethylene Chlorohydrin.
Angew Chem Int Ed Engl
; 62(13): e202216581, 2023 Mar 20.
Article
em En
| MEDLINE
| ID: mdl-36734467
ABSTRACT
Industrial manufacturing of ethylene chlorohydrin (ECH) critically requires excess corrosive hydrochloric acid or hypochlorous acid with dealing with massive by-products and wastes. Here we report a green and efficient electrosynthesis of ECH from ethylene oxide (EO) with NaCl over a NiFe2 O4 nanosheet anode. Theoretical results suggest that EO and Cl preferentially adsorb on Fe and Ni sites, respectively, collaboratively promoting the ECH synthesis. A Cl radical-mediated ring-opening process is proposed and confirmed, and the key Cl and carbon radical species are identified by high-resolution mass spectrometry. This strategy can enable scalable electrosynthesis of 185.1â
mmol of ECH in 1â
h with 92.5 % yield at a 55â
mA cm-2 current density. Furthermore, a series of other chloro- and bromoethanols with good to high yields and paired synthesis of ECH and 4-amino-3,6-dichloropyridine-2-carboxylicacid via respectively loading and unloading Cl are achieved, showing the promising potential of this strategy.
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1
Bases de dados:
MEDLINE
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China