Development and validation of an advanced <i>ex vivo</i> brain slice invasion assay to model glioblastoma cell invasion into the complex brain microenvironment.

Decotret, Lisa R; Shi, Rocky; Thomas, Kiersten N; Hsu, Manchi; Pallen, Catherine J; Bennewith, Kevin L

Development and validation of an advanced ex vivo brain slice invasion assay to model glioblastoma cell invasion into the complex brain microenvironment.

Decotret, Lisa R; Shi, Rocky; Thomas, Kiersten N; Hsu, Manchi; Pallen, Catherine J; Bennewith, Kevin L.

Afiliação

Decotret LR; Department of Integrative Oncology, BC Cancer, Vancouver, BC, Canada.
Shi R; Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Thomas KN; Department of Integrative Oncology, BC Cancer, Vancouver, BC, Canada.
Hsu M; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada.
Pallen CJ; Department of Integrative Oncology, BC Cancer, Vancouver, BC, Canada.
Bennewith KL; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada.

Front Oncol ; 13: 976945, 2023.

Article em En | MEDLINE | ID: mdl-36793608

Palavras-chave

brain microenvironment; confocal microscopy; glioblastoma multiforme; invasion; metastasis; organotypic brain slice culture

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Front Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá