Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1 gene *007 may modulate disease progression of human immunodeficiency virus-1 infection in the Japanese population.

Naruse, Taeko K; Konishi-Takemura, Makiko; Yanagida, Risa; Sharma, Gaurav; Vajpayee, Madhu; Terunuma, Hiroshi; Mehra, Narinder K; Kaur, Gurvinder; Kimura, Akinori

Naruse, Taeko K; Konishi-Takemura, Makiko; Yanagida, Risa; Sharma, Gaurav; Vajpayee, Madhu; Terunuma, Hiroshi; Mehra, Narinder K; Kaur, Gurvinder; Kimura, Akinori.

Afiliação

Naruse TK; Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Konishi-Takemura M; Department of Protozoology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Yanagida R; Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Sharma G; Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Vajpayee M; Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India.
Terunuma H; Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Mehra NK; Biotherapy Institute of Japan, Tokyo, Japan.
Kaur G; Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India.
Kimura A; Department of Transplant Immunology and Immunogenetics, All India Institute of Medical Sciences, New Delhi, India.

Int J Immunogenet ; 50(2): 48-52, 2023 Apr.

Article em En | MEDLINE | ID: mdl-36807537

ABSTRACT

ABSTRACT

One of the KIR allele, KIR3DL1*007, was associated with the progression to acquired immunodeficiency syndrome and not with the susceptibility to HIV-1 infection in the Japanese and Indian populations, implying that KIR3DL1*007-positive NK cells might eliminate HIV-infected cells less effectively than NK cells bearing the other KIR3DL1 alleles or KIR3DS1 alleles.

Assuntos

População do Leste Asiático; Infecções por HIV; Humanos; Receptores KIR3DS1/genética; Receptores KIR/genética; Infecções por HIV/genética; Alelos; Progressão da Doença; HIV/genética; Antígenos HLA-B/genética

Palavras-chave

HIV-1; KIR3DL1; NK receptors

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Infecções por HIV / População do Leste Asiático Limite: Humans Idioma: En Revista: Int J Immunogenet Assunto da revista: ALERGIA E IMUNOLOGIA / GENETICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

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