Gene expression data visualization tool on the o²S²PARC platform.
F1000Res
; 11: 1267, 2022.
Article
em En
| MEDLINE
| ID: mdl-36816807
ABSTRACT
Background:
The identification of differentially expressed genes and their associated biological processes, molecular function, and cellular components are important for genetic diseases studies because they present potential biomarkers and therapeutic targets.Methods:
In this study, we developed an o²S²PARC template representing an interactive pipeline for the gene expression data visualization and ontologies data analysis and visualization. To demonstrate the usefulness of the tool, we performed a case study on a publicly available dataset.Results:
The tool enables users to identify the differentially expressed genes (DEGs) and visualize them in a volcano plot format. The ontologies associated with the DEGs are determined and visualized in barplots.Conclusions:
The "Expression data visualization" template is publicly available on the o²S²PARC platform.Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Biologia Computacional
/
Perfilação da Expressão Gênica
Idioma:
En
Revista:
F1000Res
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Tunísia