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A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike protein-RBD-Fc vaccine, AKS-452.
Feitsma, Eline A; Janssen, Yester F; Boersma, Hendrikus H; van Sleen, Yannick; van Baarle, Debbie; Alleva, David G; Lancaster, Thomas M; Sathiyaseelan, Thillainaygam; Murikipudi, Sylaja; Delpero, Andrea R; Scully, Melanie M; Ragupathy, Ramya; Kotha, Sravya; Haworth, Jeffrey R; Shah, Nishit J; Rao, Vidhya; Nagre, Shashikant; Ronca, Shannon E; Green, Freedom M; Aminetzah, Ari; Sollie, Frans; Kruijff, Schelto; Brom, Maarten; van Dam, Gooitzen M; Zion, Todd C.
Afiliação
  • Feitsma EA; Department of Surgery, University Medical Center Groningen (UMCG), Hanzeplein 1, 9700 RB Groningen, the Netherlands.
  • Janssen YF; Department of Nuclear Medicine and Molecular Imaging, UMCG, the Netherlands.
  • Boersma HH; Department of Nuclear Medicine and Molecular Imaging, UMCG, the Netherlands; Department of Clinical Pharmacy and Pharmacology, UMCG, the Netherlands.
  • van Sleen Y; Department of Rheumatology and Clinical Immunology, UMCG, the Netherlands.
  • van Baarle D; Department of Rheumatology and Clinical Immunology, UMCG, the Netherlands.
  • Alleva DG; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Lancaster TM; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Sathiyaseelan T; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Murikipudi S; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Delpero AR; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Scully MM; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Ragupathy R; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Kotha S; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Haworth JR; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Shah NJ; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Rao V; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Nagre S; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States.
  • Ronca SE; Department of Pediatrics, Division of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Baylor, College of Medicine, 1102 Bates Ave, 300.15, Houston, TX 77030, United States.
  • Green FM; Department of Pediatrics, Division of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Baylor, College of Medicine, 1102 Bates Ave, 300.15, Houston, TX 77030, United States.
  • Aminetzah A; TRACER BV, L.J. Zielstraweg 1, 9766 GX Groningen, the Netherlands.
  • Sollie F; ICON, van Swietenlaan 6, 9728 NZ Groningen, the Netherlands.
  • Kruijff S; Department of Surgery, University Medical Center Groningen (UMCG), Hanzeplein 1, 9700 RB Groningen, the Netherlands; Department of Nuclear Medicine and Molecular Imaging, UMCG, the Netherlands.
  • Brom M; TRACER BV, L.J. Zielstraweg 1, 9766 GX Groningen, the Netherlands.
  • van Dam GM; Department of Nuclear Medicine and Molecular Imaging, UMCG, the Netherlands; TRACER BV, L.J. Zielstraweg 1, 9766 GX Groningen, the Netherlands.
  • Zion TC; Akston Biosciences Corporation., 100 Cummings Center, Suite 454C, Beverly, MA 01915, United States. Electronic address: todd.zion@akstonbio.com.
Vaccine ; 41(13): 2184-2197, 2023 03 24.
Article em En | MEDLINE | ID: mdl-36842886
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Vaccine Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Vaccine Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda