A new intronic quantitative PCR method led to the discovery of transformation from human ascites to murine malignancy in a mouse model.

Jin, Jiankang; Huo, Longfei; Fan, Yibo; Wang, Ruiping; Scott, Ailing W; Pizzi, Melissa Pool; Yao, Xiaodan; Shao, Shan; Ma, Lang; Da Silva, Matheus S; Yamashita, Kohei; Yoshimura, Katsuhiro; Zhang, Boyu; Wu, Jingjing; Wang, Linghua; Song, Shumei; Ajani, Jaffer A

Jin, Jiankang; Huo, Longfei; Fan, Yibo; Wang, Ruiping; Scott, Ailing W; Pizzi, Melissa Pool; Yao, Xiaodan; Shao, Shan; Ma, Lang; Da Silva, Matheus S; Yamashita, Kohei; Yoshimura, Katsuhiro; Zhang, Boyu; Wu, Jingjing; Wang, Linghua; Song, Shumei; Ajani, Jaffer A.

Afiliação

Jin J; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Huo L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Fan Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Wang R; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Scott AW; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Pizzi MP; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Yao X; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Shao S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Ma L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Da Silva MS; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Yamashita K; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Yoshimura K; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Zhang B; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Wu J; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Song S; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Ajani JA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Front Oncol ; 13: 1062424, 2023.

Article em En | MEDLINE | ID: mdl-36865791

Palavras-chave

authentication and quantification of human and murine samples; human-to-murine oncogenic transformation; intronic genomic qPCR; patient-derived xenograft (PDX); tumor microenvironment (TME); whole exosome sequencing (WES)

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Front Oncol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos