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Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants.
Kim, Ji Woong; Heo, Kyun; Kim, Hyun Jung; Yoo, Youngki; Cho, Hyun-Soo; Jang, Hui Jeong; Lee, Ho-Young; Ko, In Young; Woo, Ju Rang; Cho, Yea Bin; Lee, Ji Hyun; Yang, Ha Rim; Shin, Ha Gyeong; Choi, Hye Lim; Hwang, Kyusang; Kim, Sokho; Kim, Hanseong; Chun, Kwangrok; Lee, Sukmook.
Afiliação
  • Kim JW; Department of Biochemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Heo K; Department of Biochemistry, Kookmin University, Seoul, 02707, Republic of Korea; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea; Antibody Research Institute, Kookmin University, Seoul, 02707, Republic of Korea.
  • Kim HJ; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Yoo Y; Department of Systems Biology, Yonsei University, Seoul, 03722, Republic of Korea.
  • Cho HS; Department of Systems Biology, Yonsei University, Seoul, 03722, Republic of Korea.
  • Jang HJ; Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul, 13620, Republic of Korea.
  • Lee HY; Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul, 13620, Republic of Korea.
  • Ko IY; New Drug Development Center, KBIOHealth, Cheongju, 28160, Republic of Korea.
  • Woo JR; New Drug Development Center, KBIOHealth, Cheongju, 28160, Republic of Korea.
  • Cho YB; Department of Biochemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Lee JH; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Yang HR; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Shin HG; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Choi HL; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Hwang K; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea.
  • Kim S; Research Center, KNOTUS Co. Ltd., Incheon, 22014, Republic of Korea.
  • Kim H; Baobab AiBIO, POSCO Green Building, Yonsei University, Incheon, 21983, Republic of Korea.
  • Chun K; R&D Center, Binex, Incheon, 21999, Republic of Korea.
  • Lee S; Department of Biochemistry, Kookmin University, Seoul, 02707, Republic of Korea; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul, 02707, Republic of Korea; Antibody Research Institute, Kookmin University, Seoul, 02707, Republic of Korea. Electronic address: lees2018@kookmin.ac.k
Antiviral Res ; 212: 105576, 2023 04.
Article em En | MEDLINE | ID: mdl-36870394
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / COVID-19 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Antiviral Res Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos / COVID-19 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Antiviral Res Ano de publicação: 2023 Tipo de documento: Article