Avoiding background knowledge: literature based discovery from important information.
BMC Bioinformatics
; 23(Suppl 9): 570, 2023 Mar 14.
Article
em En
| MEDLINE
| ID: mdl-36918777
ABSTRACT
BACKGROUND:
Automatic literature based discovery attempts to uncover new knowledge by connecting existing facts information extracted from existing publications in the form of [Formula see text] and [Formula see text] relations can be simply connected to deduce [Formula see text]. However, using this approach, the quantity of proposed connections is often too vast to be useful. It can be reduced by using subject[Formula see text](predicate)[Formula see text]object triples as the [Formula see text] relations, but too many proposed connections remain for manual verification.RESULTS:
Based on the hypothesis that only a small number of subject-predicate-object triples extracted from a publication represent the paper's novel contribution(s), we explore using BERT embeddings to identify these before literature based discovery is performed utilizing only these, important, triples. While the method exploits the availability of full texts of publications in the CORD-19 dataset-making use of the fact that a novel contribution is likely to be mentioned in both an abstract and the body of a paper-to build a training set, the resulting tool can be applied to papers with only abstracts available. Candidate hidden knowledge pairs generated from unfiltered triples and those built from important triples only are compared using a variety of timeslicing gold standards.CONCLUSIONS:
The quantity of proposed knowledge pairs is reduced by a factor of [Formula see text], and we show that when the gold standard is designed to avoid rewarding background knowledge, the precision obtained increases up to a factor of 10. We argue that the gold standard needs to be carefully considered, and release as yet undiscovered candidate knowledge pairs based on important triples alongside this work.Palavras-chave
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Bases de dados:
MEDLINE
Assunto principal:
Conhecimento
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Descoberta do Conhecimento
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
BMC Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Reino Unido