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Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Jia, Ruifang; Zhang, Jiwei; Shi, Fangyuan; Bonomini, Anna; Lucca, Camilla; Bertagnin, Chiara; Zhang, Jian; Liu, Chuanfeng; Jia, Huinan; Jiang, Yuanmin; Ma, Xiuli; Loregian, Arianna; Huang, Bing; Zhan, Peng; Liu, Xinyong.
Afiliação
  • Jia R; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
  • Zhang J; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
  • Shi F; Department of Pharmacy, Qilu Hospital, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
  • Bonomini A; Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121, Padova, Italy.
  • Lucca C; Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121, Padova, Italy.
  • Bertagnin C; Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121, Padova, Italy.
  • Zhang J; Institute of Medical Sciences, The Second Hospital, Shandong University, 247 Beiyuan Street, 250033, Jinan, Shandong, PR China.
  • Liu C; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
  • Jia H; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
  • Jiang Y; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China.
  • Ma X; Institute of Poultry Science, Shandong Academy of Agricultural Sciences, 1 Jiaoxiao Road, Jinan, Shandong, 250023, PR China.
  • Loregian A; Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121, Padova, Italy.
  • Huang B; Institute of Poultry Science, Shandong Academy of Agricultural Sciences, 1 Jiaoxiao Road, Jinan, Shandong, 250023, PR China. Electronic address: hbind@163.com.
  • Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Anti
  • Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 West Culture Road, 250012, Jinan, Shandong, PR China; China-Belgium Collaborative Research Center for Innovative Anti
Eur J Med Chem ; 252: 115275, 2023 Apr 05.
Article em En | MEDLINE | ID: mdl-36931117
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Vírus da Influenza A Subtipo H1N1 / Virus da Influenza A Subtipo H5N1 Tipo de estudo: Prognostic_studies Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Vírus da Influenza A Subtipo H1N1 / Virus da Influenza A Subtipo H5N1 Tipo de estudo: Prognostic_studies Idioma: En Revista: Eur J Med Chem Ano de publicação: 2023 Tipo de documento: Article