In vivo endoscopic ultrasound imaging with a rotational-scanning, all-optical ultrasound probe.
Opt Lett
; 48(7): 1926-1929, 2023 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-37221801
ABSTRACT
All-optical ultrasound manipulates ultrasound waves based on laser and photonics technologies, providing an alternative approach for pulse-echo ultrasound imaging. However, its endoscopic imaging capability is limited ex vivo by the multifiber connection between the endoscopic probe and the console. Here, we report on all-optical ultrasound for in vivo endoscopic imaging using a rotational-scanning probe that relies on a small laser sensor to detect echo ultrasound waves. The acoustically induced lasing frequency change is measured via heterodyne detection by beating the two orthogonally polarized laser modes, enabling a stable output of ultrasonic responses and immunity to low-frequency thermal and mechanical disturbances. We miniaturize its optical driving and signal interrogation unit and synchronously rotate it with the imaging probe. This specialized design leaves a single-fiber connection to the proximal end and allows fast rotational scanning of the probe. As a result, we used a flexible, miniature all-optical ultrasound probe for in vivo rectal imaging with a B-scan rate of 1â
Hz and a pullback range of â¼7â
cm. This can visualize the gastrointestinal and extraluminal structures of a small animal. This imaging modality offers an imaging depth of 2â
cm at a central frequency of â¼20â
MHz, showing promise for high-frequency ultrasound imaging applications in gastroenterology and cardiology.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Diagnóstico por Imagem
/
Folhas de Planta
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Opt Lett
Ano de publicação:
2023
Tipo de documento:
Article