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Novel SARS-CoV-2 entry inhibitors, 2-anilinoquinazolin-4(3H)-one derivatives, show potency as SARS-CoV-2 antivirals in a human ACE2 transgenic mouse model.
Ko, Meehyun; Lee, Jun Young; Shin, Young Sup; Jeon, Sangeun; Myung, Subeen; Cho, Jung-Eun; Jang, Min Seong; Song, Jong Hwan; Kim, Hyoung Rae; Park, Hyeung-Geun; Park, Chul Min; Kim, Seungtaek.
Afiliação
  • Ko M; Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, Republic of Korea.
  • Lee JY; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.
  • Shin YS; Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
  • Jeon S; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.
  • Myung S; Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
  • Cho JE; Zoonotic Virus Laboratory, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, Republic of Korea.
  • Jang MS; Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
  • Song JH; Medicinal Chemistry and Pharmacology, University of Science and Technology, Daejeon, Republic of Korea.
  • Kim HR; Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
  • Park HG; Department of Non-Clinical Studies, Korea Institute of Toxicology, Daejeon, Republic of Korea.
  • Park CM; Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
  • Kim S; Center for Convergent Research of Emerging Virus Infection (CEVI), Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
J Med Virol ; 95(6): e28863, 2023 06.
Article em En | MEDLINE | ID: mdl-37310127
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: J Med Virol Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: J Med Virol Ano de publicação: 2023 Tipo de documento: Article