Uridine Derivatives: Synthesis, Biological Evaluation, and In Silico Studies as Antimicrobial and Anticancer Agents.

Munia, Nasrin S; Alanazi, Mohammed M; El Bakri, Youness; Alanazi, Ashwag S; Mukhrish, Yousef E; Hasan, Imtiaj; Kawsar, Sarkar M A

Munia, Nasrin S; Alanazi, Mohammed M; El Bakri, Youness; Alanazi, Ashwag S; Mukhrish, Yousef E; Hasan, Imtiaj; Kawsar, Sarkar M A.

Afiliação

Munia NS; Laboratory of Carbohydrate and Nucleoside Chemistry (LCNC), Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong 4331, Bangladesh.
Alanazi MM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
El Bakri Y; Department of Theoretical and Applied Chemistry, South Ural State University, Lenin prospect 76, Chelyabinsk 454080, Russia.
Alanazi AS; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Mukhrish YE; Department of Chemistry, Faculty of Science, Jazan University, P.O. Box 2097, Jazan 45142, Saudi Arabia.
Hasan I; Department of Biochemistry and Molecular Biology, Faculty of Science, University of Rajshahi, Rajshahi 6205, Bangladesh.
Kawsar SMA; Laboratory of Carbohydrate and Nucleoside Chemistry (LCNC), Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong 4331, Bangladesh.

Medicina (Kaunas) ; 59(6)2023 Jun 07.

Article em En | MEDLINE | ID: mdl-37374310

Assuntos

Anti-Infecciosos; Antineoplásicos; Humanos; Estrutura Molecular; Uridina/farmacologia; Uridina/uso terapêutico; Simulação de Acoplamento Molecular; Nucleosídeos/farmacologia; Nucleosídeos/uso terapêutico; Anti-Infecciosos/farmacologia; Anti-Infecciosos/uso terapêutico; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Bactérias; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico

Palavras-chave

antimicrobial agents; antiproliferative; cytotoxicity; molecular docking; molecular dynamics; pharmacokinetics; uridine derivatives

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Anti-Infecciosos / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Medicina (Kaunas) Assunto da revista: MEDICINA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Bangladesh

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