Shear Stress Drives the Cleavage Activation of Protease-Activated Receptor 2 by PRSS3/Mesotrypsin to Promote Invasion and Metastasis of Circulating Lung Cancer Cells.

Zhou, Muya; Li, Koukou; Luo, Kathy Qian

Zhou, Muya; Li, Koukou; Luo, Kathy Qian.

Afiliação

Zhou M; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macao SAR, 999078, China.
Li K; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macao SAR, 999078, China.
Luo KQ; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macao SAR, 999078, China.

Adv Sci (Weinh) ; 10(25): e2301059, 2023 09.

Article em En | MEDLINE | ID: mdl-37395651

Assuntos

Neoplasias Pulmonares; Células Neoplásicas Circulantes; Humanos; Linhagem Celular Tumoral; Neoplasias Pulmonares/patologia; Células Neoplásicas Circulantes/patologia; Receptor PAR-2; Receptores Acoplados a Proteínas G; Tripsina/metabolismo

Palavras-chave

PRSS3/mesotrypsin; cancer metastasis; circulating tumor cells; protease-activated receptor 2; shear stress

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Neoplasias Pulmonares / Células Neoplásicas Circulantes Limite: Humans Idioma: En Revista: Adv Sci (Weinh) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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