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Impaired dynamic X-chromosome inactivation maintenance in T cells is a feature of spontaneous murine SLE that is exacerbated in female-biased models.
Jiwrajka, Nikhil; Toothacre, Natalie E; Beethem, Zachary T; Sting, Sarah; Forsyth, Katherine S; Dubin, Aimee H; Driscoll, Amanda; Stohl, William; Anguera, Montserrat C.
Afiliação
  • Jiwrajka N; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA; Division of Rheumatology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
  • Toothacre NE; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
  • Beethem ZT; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
  • Sting S; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
  • Forsyth KS; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
  • Dubin AH; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
  • Driscoll A; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.
  • Stohl W; Division of Rheumatology, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.
  • Anguera MC; Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA. Electronic address: anguera@vet.upenn.edu.
J Autoimmun ; 139: 103084, 2023 09.
Article em En | MEDLINE | ID: mdl-37399593
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Linfócitos T / Autoimunidade / Inativação do Cromossomo X / Lúpus Eritematoso Sistêmico Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Linfócitos T / Autoimunidade / Inativação do Cromossomo X / Lúpus Eritematoso Sistêmico Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos