CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm <i>Fusarium graminearum</i> C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones.

Hicks, Carmen; Witte, Thomas E; Sproule, Amanda; Hermans, Anne; Shields, Samuel W; Colquhoun, Ronan; Blackman, Chris; Boddy, Christopher N; Subramaniam, Rajagopal; Overy, David P

CRISPR-Cas9 Gene Editing and Secondary Metabolite Screening Confirm Fusarium graminearum C16 Biosynthetic Gene Cluster Products as Decalin-Containing Diterpenoid Pyrones.

Hicks, Carmen; Witte, Thomas E; Sproule, Amanda; Hermans, Anne; Shields, Samuel W; Colquhoun, Ronan; Blackman, Chris; Boddy, Christopher N; Subramaniam, Rajagopal; Overy, David P.

Afiliação

Hicks C; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Witte TE; Department of Chemistry & Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Sproule A; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Hermans A; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Shields SW; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Colquhoun R; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Blackman C; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Boddy CN; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.
Subramaniam R; Department of Chemistry & Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Overy DP; Ottawa Research & Development Centre, Agriculture & Agri-Food Canada, 960 Carling Ave., Ottawa, ON K1A 0C6, Canada.

J Fungi (Basel) ; 9(7)2023 Jun 23.

Article em En | MEDLINE | ID: mdl-37504684

Palavras-chave

CRISPR-Cas9; Fusarium Head Blight; Fusarium graminearum; gene editing; secondary metabolism; virulence factor; wheat pathogen

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Texto completo: 1 Bases de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: J Fungi (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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