Ticlopidine induces embryonic development toxicity and hepatotoxicity in zebrafish by upregulating the oxidative stress signaling pathway.

Xu, Rong; Xu, Pengxiang; Wei, Haiyan; Huang, Yong; Zhu, Xiaodan; Lin, Chuanming; Yan, Zhimin; Xin, Liuyan; Li, Lin; Lv, Weiming; Zeng, Shuqin; Tian, Guiyou; Ma, Jinze; Cheng, Bo; Lu, Huiqiang; Chen, Yijian

Xu, Rong; Xu, Pengxiang; Wei, Haiyan; Huang, Yong; Zhu, Xiaodan; Lin, Chuanming; Yan, Zhimin; Xin, Liuyan; Li, Lin; Lv, Weiming; Zeng, Shuqin; Tian, Guiyou; Ma, Jinze; Cheng, Bo; Lu, Huiqiang; Chen, Yijian.

Afiliação

Xu R; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Xu P; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Wei H; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Huang Y; State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330029, Jiangxi, PR China.
Zhu X; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Lin C; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Yan Z; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Xin L; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Li L; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Lv W; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Zeng S; The First Affiliated Hospital of Gannan Medical University, Ganzhou 341000 Jiangxi, PR China.
Tian G; Ganzhou Key Laboratory for Drug Screening and Discovery, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000 Jiangxi, PR China.
Ma J; Ganzhou Key Laboratory for Drug Screening and Discovery, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000 Jiangxi, PR China.
Cheng B; Ganzhou Key Laboratory for Drug Screening and Discovery, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000 Jiangxi, PR China.
Lu H; Ganzhou Key Laboratory for Drug Screening and Discovery, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000 Jiangxi, PR China. Electronic address: luhq2@126.com.
Chen Y; The First Afï¬liated Hospital of Gannan Medical University, Ganzhou 341000, China; The Endemic Disease (Thalassemia) Clinical Research Center of Jiangxi Province, Ganzhou 341000, China. Electronic address: chenyj2005@163.com.

Ecotoxicol Environ Saf ; 262: 115283, 2023 Jul 31.

Article em En | MEDLINE | ID: mdl-37531924

Palavras-chave

Hepatotoxicity; N-acetylcysteine; Oxidative stress; Ticlopidine; Zebrafish

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Texto completo: 1 Bases de dados: MEDLINE Idioma: En Revista: Ecotoxicol Environ Saf Ano de publicação: 2023 Tipo de documento: Article