CRISPR-Cas9 Activities with Truncated 16-Nucleotide RNA Guides Are Tuned by Target Duplex Stability Beyond the RNA/DNA Hybrid.

Li, Yue; Cooper, Brendon H; Liu, Yukang; Wu, Difei; Zhang, Xiaojun; Rohs, Remo; Qin, Peter Z

Li, Yue; Cooper, Brendon H; Liu, Yukang; Wu, Difei; Zhang, Xiaojun; Rohs, Remo; Qin, Peter Z.

Afiliação

Li Y; Department of Chemistry, University of Southern California, Los Angeles, California 90089, United States.
Cooper BH; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, California 90089, United States.
Liu Y; Department of Chemistry, University of Southern California, Los Angeles, California 90089, United States.
Wu D; Department of Chemistry, University of Southern California, Los Angeles, California 90089, United States.
Zhang X; Department of Chemistry, University of Southern California, Los Angeles, California 90089, United States.
Rohs R; Department of Chemistry, University of Southern California, Los Angeles, California 90089, United States.
Qin PZ; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, California 90089, United States.

Biochemistry ; 62(17): 2541-2548, 2023 09 05.

Article em En | MEDLINE | ID: mdl-37552860

Assuntos

Sistemas CRISPR-Cas; RNA; RNA/genética; Nucleotídeos; DNA/genética; Edição de Genes/métodos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: RNA / Sistemas CRISPR-Cas Idioma: En Revista: Biochemistry Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google