Health Digital Twins in Life Science and Health Care Innovation.
Annu Rev Pharmacol Toxicol
; 64: 159-170, 2024 Jan 23.
Article
em En
| MEDLINE
| ID: mdl-37562495
ABSTRACT
Health digital twins (HDTs) are virtual representations of real individuals that can be used to simulate human physiology, disease, and drug effects. HDTs can be used to improve drug discovery and development by providing a data-driven approach to inform target selection, drug delivery, and design of clinical trials. HDTs also offer new applications into precision therapies and clinical decision making. The deployment of HDTs at scale could bring a precision approach to public health monitoring and intervention. Next steps include challenges such as addressing socioeconomic barriers and ensuring the representativeness of the technology based on the training and validation data sets. Governance and regulation of HDT technology are still in the early stages.
Palavras-chave
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Disciplinas das Ciências Biológicas
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Annu Rev Pharmacol Toxicol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos