Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog.

Dai, Mei-Jie; Gui, Xing-Xing; Jia, Shu-Miao; Lv, Shu-Ting; Dou, Hao; Cui, Wei

Dai, Mei-Jie; Gui, Xing-Xing; Jia, Shu-Miao; Lv, Shu-Ting; Dou, Hao; Cui, Wei.

Afiliação

Dai MJ; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Gui XX; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Jia SM; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Lv ST; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Dou H; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Cui W; Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110016, China. cuiwei@syphu.edu.cn.

Acta Pharmacol Sin ; 44(12): 2404-2417, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37580491

Assuntos

AVC Isquêmico; Acidente Vascular Cerebral; Camundongos; Humanos; Animais; Proteínas Hedgehog/metabolismo; Células Endoteliais da Veia Umbilical Humana/metabolismo; Acidente Vascular Cerebral/tratamento farmacológico

Palavras-chave

Dl-3-n-butylphthalide; angiogenesis; brain ischemia/ reperfusion; hedgehog signaling pathway; ischemic stroke; tMCAO model

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Acidente Vascular Cerebral / AVC Isquêmico Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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