Inhibition of ERK downregulates autophagy via mitigating mitochondrial fragmentation to protect SH-SY5Y cells from OGD/R injury.

Yuan, Zhang-Li; Mo, Yan-Zi; Li, De-Li; Xie, Lu; Chen, Meng-Hua

Yuan, Zhang-Li; Mo, Yan-Zi; Li, De-Li; Xie, Lu; Chen, Meng-Hua.

Afiliação

Yuan ZL; Department of Emergency Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, Guangxi, People's Republic of China.
Mo YZ; Intensive Care Unit, The Second Affiliated Hospital of Guangxi Medical University, 166 Daxuedong Road, Guangxi, 530007, Nanning, People's Republic of China.
Li DL; Guangxi Medical University, 22 Shuangyong Road, Guangxi, 530021, Nanning, People's Republic of China.
Xie L; Guangxi Medical University, 22 Shuangyong Road, Guangxi, 530021, Nanning, People's Republic of China. xielu8282@163.com.
Chen MH; Intensive Care Unit, The Second Affiliated Hospital of Guangxi Medical University, 166 Daxuedong Road, Guangxi, 530007, Nanning, People's Republic of China. xyicucmh@sina.com.

Cell Commun Signal ; 21(1): 204, 2023 08 14.

Article em En | MEDLINE | ID: mdl-37580749

Assuntos

Neuroblastoma; Oxigênio; Humanos; Oxigênio/metabolismo; MAP Quinases Reguladas por Sinal Extracelular; Apoptose; Glucose/metabolismo; Dinaminas; Autofagia

Palavras-chave

Autophagy; CIRI; Drp1; ERK; Mfn2; Mitochondrial dynamics; OGD/R

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Oxigênio / Neuroblastoma Limite: Humans Idioma: En Revista: Cell Commun Signal Ano de publicação: 2023 Tipo de documento: Article

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