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Targeting Cytotoxic Agents through EGFR-Mediated Covalent Binding and Release.
Morese, Pasquale A; Anthony, Nahoum; Bodnarchuk, Michael; Jennings, Claire; Martin, Mathew P; Noble, Richard A; Phillips, Nicole; Thomas, Huw D; Wang, Lan Z; Lister, Andrew; Noble, Martin E M; Ward, Richard A; Wedge, Stephen R; Stewart, Hannah L; Waring, Michael J.
Afiliação
  • Morese PA; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Chemistry, School of Natural and Environmental Sciences, Newcastle University, Bedson Building, Newcastle upon Tyne NE1 7RU, U.K.
  • Anthony N; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Bodnarchuk M; Oncology iMed, R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Jennings C; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Martin MP; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Noble RA; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Phillips N; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Thomas HD; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Lister A; Oncology iMed, R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Noble MEM; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Ward RA; Oncology iMed, R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
  • Wedge SR; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Faculty of Medical Sciences, Paul O'Gorman Building, Newcastle University, Newcastle upon Tyne NE2 4HH, U.K.
  • Stewart HL; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Chemistry, School of Natural and Environmental Sciences, Newcastle University, Bedson Building, Newcastle upon Tyne NE1 7RU, U.K.
  • Waring MJ; Cancer Research Horizons Therapeutic Innovation, Newcastle University Centre for Cancer, Chemistry, School of Natural and Environmental Sciences, Newcastle University, Bedson Building, Newcastle upon Tyne NE1 7RU, U.K.
J Med Chem ; 66(17): 12324-12341, 2023 09 14.
Article em En | MEDLINE | ID: mdl-37647129
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Citotoxinas / Fluoruracila Tipo de estudo: Prognostic_studies Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Citotoxinas / Fluoruracila Tipo de estudo: Prognostic_studies Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido