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2-Hydroxyethyl methacrylate (HEMA): A clinical review of contact allergy and allergic contact dermatitis-Part 1. Introduction, epidemiology, case series and case reports.
de Groot, Anton C; Rustemeyer, Thomas.
Afiliação
  • de Groot AC; Schipslootweg 5, Wapserveen, The Netherlands.
  • Rustemeyer T; Dermato-Allergology and Occupational Dermatology, Amsterdam University Medical Centers, Amsterdam, AZ, The Netherlands.
Contact Dermatitis ; 89(6): 401-433, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37752620
ABSTRACT
2-Hydroxyethyl methacrylate (HEMA) has been increasingly recognised as a contact allergen and was added to the European baseline series in 2019. In this article (2 parts), the results of an extensive literature review of the clinical aspects of contact allergy/allergic contact dermatitis to HEMA are presented. In part 1, the epidemiology of HEMA contact allergy is discussed and detailed information on published case series and case reports presented. HEMA is an important cause of contact allergy/allergic contact dermatitis in North America and Europe with recent prevalences of >3% in the USA + Canada and 1.5%-3.7% in Europe. Currently, most cases are caused by nail cosmetics, both in consumers and professional nail stylists. In our literature review, we have found 24 studies presenting case series of patients with allergic contact dermatitis attributed to HEMA and 168 case reports. However, the presence of HEMA in the products causing ACD was established in only a minority. Part 2 will discuss cross- and co-sensitisation, and other skin reactions to HEMA, will assess whether HEMA is the most frequent (meth)acrylate allergen and how sensitive HEMA as a screening agent is, investigate the presence of HEMA in commercial products and provide practical information on patch testing procedures.
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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Dermatite Alérgica de Contato / Dermatite Ocupacional Tipo de estudo: Screening_studies Limite: Humans Idioma: En Revista: Contact Dermatitis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Dermatite Alérgica de Contato / Dermatite Ocupacional Tipo de estudo: Screening_studies Limite: Humans Idioma: En Revista: Contact Dermatitis Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda