Optimization of Peripheral Blood Mononuclear Cell Processing for Improved Clinical ELISpot Assay Performance.

Li, Xinyuan; He, Shan; Thomas, Jaya; Wu, Bonnie; Yang, Tong-Yuan; Swanson, Michael

Li, Xinyuan; He, Shan; Thomas, Jaya; Wu, Bonnie; Yang, Tong-Yuan; Swanson, Michael.

Afiliação

Li X; Janssen Research & Development LLC., 1400 McKean Road, Spring House, Pennsylvania, 19477, USA. xli323@its.jnj.com.
He S; Janssen Research & Development LLC., 1400 McKean Road, Spring House, Pennsylvania, 19477, USA.
Thomas J; Janssen Research & Development LLC., 1400 McKean Road, Spring House, Pennsylvania, 19477, USA.
Wu B; Janssen Research & Development LLC., 1400 McKean Road, Spring House, Pennsylvania, 19477, USA.
Yang TY; Janssen Research & Development LLC., 1400 McKean Road, Spring House, Pennsylvania, 19477, USA.
Swanson M; Janssen Research & Development LLC., 1400 McKean Road, Spring House, Pennsylvania, 19477, USA.

AAPS J ; 25(6): 93, 2023 09 28.

Article em En | MEDLINE | ID: mdl-37770755

Assuntos

Interferon gama; Leucócitos Mononucleares; Humanos; ELISPOT/métodos; Imunidade Celular

Palavras-chave

ELISpot; PBMC; SepMate; cell therapy; cellular immunogenicity; clinical trial; gene therapy; peripheral blood mononuclear cells; vaccine

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Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Interferon gama Limite: Humans Idioma: En Revista: AAPS J Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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