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A mitochondria-targeted far-red AIE fluorescent probe for distinguishing between mitophagy and ferroptosis in cancer cells.
Sun, Liyuan; Zou, Mengfei; Du, Longjie; Wang, Shugang; Ding, Ru; Lu, Keliang; Li, Jianchun; Zhou, Jin.
Afiliação
  • Sun L; School of Pharmacy, School of Anesthesiology, School of Nursing, Weifang Medical University, Weifang, 261053, China. zhoujin@wfmc.edu.cn.
  • Zou M; School of Pharmacy, School of Anesthesiology, School of Nursing, Weifang Medical University, Weifang, 261053, China. zhoujin@wfmc.edu.cn.
  • Du L; Weifang People's Hospital, Weifang, 261041, China.
  • Wang S; School of Pharmacy, School of Anesthesiology, School of Nursing, Weifang Medical University, Weifang, 261053, China. zhoujin@wfmc.edu.cn.
  • Ding R; Department of Rheumatology, Weifang Hospital of Traditional Chinese Medicine, Weifang, 261000, China.
  • Lu K; School of Pharmacy, School of Anesthesiology, School of Nursing, Weifang Medical University, Weifang, 261053, China. zhoujin@wfmc.edu.cn.
  • Li J; School of Pharmacy, School of Anesthesiology, School of Nursing, Weifang Medical University, Weifang, 261053, China. zhoujin@wfmc.edu.cn.
  • Zhou J; School of Pharmacy, School of Anesthesiology, School of Nursing, Weifang Medical University, Weifang, 261053, China. zhoujin@wfmc.edu.cn.
Chem Commun (Camb) ; 59(85): 12735-12738, 2023 Oct 24.
Article em En | MEDLINE | ID: mdl-37800994
ABSTRACT
A mitochondria-targeted far-red fluorescent probe LY-1 with AIE character was formulated to track cell viscosity alterations with excellent sensitivity and selectivity, which was used to discriminate between mitophagy and ferroptosis in cancer cells. Probe LY-1 is expected to be an effective vehicle for the diagnosis of mitochondrial viscosity relevant diseases.
Assuntos

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ferroptose / Neoplasias Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Bases de dados: MEDLINE Assunto principal: Ferroptose / Neoplasias Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China